Can we prevent the transmission of inherited genetic mutations that cause breast cancer?
That is the question to my first crowd-funding project on Micryoryza, as I try to determine whether PARP inhibitors can be used to prevent the production of BRCA mutant gametes that are believed to cause breast cancer. If the study is funded, and the outcome successful, we may have identified a new mechanism by which to prevent the transmission of genetic mutations from parents to their offspring.
The study also highlights a new paradigm for funding potentially high-impact research. Through Microryza, members of the public will be able to directly contribute to the research study, and follow real-time updates on the status of the project. I will be able to provide live updates detailing the experimental design, the results of each stage of the project, and overall outcomes of the study.
And through Science Exchange, of which I am a co-founder, I will be able to access experts and resources at the UNC Animal Models Core who can actually perform the study. This will allow me to focus on the experimental design and data analysis, while saving on significant up-front capital costs and turn-around time.
The combined ability to operate a virtual lab through Science Exchange, and funded through Microryza, truly affords a new way for scientists outside the traditional academic system to make ground-breaking discoveries.
If you are interested in learning more about the project, please visit the link at: www.microryza.com/projects/can-we-prevent-the-transmission-of-brca-mutations
Appreciate your support!
[about_box image=”http://thebenchapp.s3.amazonaws.com/wp-content/uploads/2012/03/Elizabeth-80.png”]Elizabeth Iorns is Co-Founder & CEO of Science Exchange. Elizabeth conceived the idea for Science Exchange while an Assistant Professor at the University of Miami and as CEO she drives the company’s vision, strategy and growth. She is passionate about creating a new way to foster scientific collaboration that will break down existing silos, democratize access to scientific expertise and accelerate the speed of scientific discovery. Elizabeth has a B.S. in Biomedical Science from the University of Auckland, a Ph.D. in Cancer Biology from the Institute of Cancer Research in London, and conducted postdoctoral research in Cancer Biology from the University of Miami’s Miller School of Medicine where her research focused on identifying mechanisms of breast cancer development and progression.[/about_box]