June 12, 2013 | Posted by Dan in Science Exchange News |

It’s been a great couple of months for Science Exchange, with significant growth in the marketplace and an injection of new capital from amazing VC partners.

And yet despite this growth, the Science Exchange team has remained lean. Very lean. Too lean. Our team of five passionate, dedicated people has achieved a lot in the last 18 months, but we knew further growth would require hiring more great people to join us.

So since April we’ve been recruiting and interviewing like crazy to find the right people to join our team. Hiring at a startup is hard. Identifying, vetting and securing talent is a full-time job. And, given Science Exchange is still small, there is no room for error… we need A-level talent in every position.

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ACGT – Clinical Applications for Next Generation Sequencing

June 10, 2013 | Posted by Guest in Education |

This is a guest post by David Cook, Legal Counsel at ACGT, Inc.

Next Generation Sequencing (NGS) holds the exciting promise of a real world integration of genomics into medicine.  While the use of this technology in clinical applications is at a nascent stage, DNA sequencing providers have been adapting their NGS services to meet the needs of a new clinician clientele.

ACGT, Inc., a Chicago-based sequencing provider, will also begin offering clinical NGS services with the anticipated launch of ACGT, Inc. Molecular Diagnostics in late 2013.

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Techniques Series: RNA Extraction

June 6, 2013 | Posted by Mamata Thapa in Research |


RNA extraction involves a series of steps for the isolation of RNA from biological molecules. The final product is used for experiments such as qRT-PCR, microarray, next-generation sequencing, or Northerns.

This technique can aid scientists into addressing a wide range of questions. For instance, what may be the level of mRNA expression of a gene involved in the developmental stage of an invasive insect species? Which steps of rRNA processing are affected in cells depleted of cell cycle proteins? What modifications in tRNAs lead to certain autoimmune diseases? This technique is applicable in a wide range of organismal groups extending from bacteria to humans.

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