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ACGT – Clinical Applications for Next Generation Sequencing

This is a guest post by David Cook, Legal Counsel at ACGT, Inc.

Next Generation Sequencing (NGS) holds the exciting promise of a real world integration of genomics into medicine.  While the use of this technology in clinical applications is at a nascent stage, DNA sequencing providers have been adapting their NGS services to meet the needs of a new clinician clientele.

ACGT, Inc., a Chicago-based sequencing provider, will also begin offering clinical NGS services with the anticipated launch of ACGT, Inc. Molecular Diagnostics in late 2013.

History of ACGT, Inc.

Known for the excellence and quality of its Sanger DNA sequencing service, ACGT, Inc. was founded in 1993 by Heron Yu, Ph.D.  Headquarters are based in the north suburbs of Chicago, Illinois, with a satellite facility near Bethesda, Maryland to service the National Institute of Health and our east coast customers.

Building on our core service of Sanger sequencing, today ACGT, Inc. provides a comprehensive suite of genetic and genomic analysis services, which includes cloning, genotyping, gene expression, plasmid preparation and NGS.  All services are available under GLP protocols.

Certified Next Generation Sequencing

2013 represents an important and pivotal year for ACGT, Inc, marking its 20th anniversary.

The year also presents important developments and investment in new technologies. ACGT, Inc. has heavily invested in NGS services with an upgrade to the MiSeq™, the most up-to-date Illumina NGS platform.  We have sought accreditation with CAP (The College of American Pathologists) to be certified as a CLIA-compliant provider (Clinical Laboratory Improvement Amendments).  With a successful inspection in March of this year, along with a verbal recommendation for certification, we anticipate accreditation by the end of 2013.  Lastly, with the growing demand for our NGS services, ACGT, Inc. has acquired a highly regarded clinical bioinformatician to direct our NGS services and the clinical services of ACGT, Inc. Molecular Diagnostics.

Services for Order on ACGT, Inc.

Going forward, our expectation is that ACGT, Inc. will provide the scientific and medical communities with the same quality and reliable NGS services they have come to expect with our Sanger sequencing and molecular biology services.  For more information on ACGT, Inc., or to order any of these services, visit

Above, you can also watch a short video of Jim Lund of ACGT, Inc. explain DNA sequencing by Sanger and Next Generation Sequencing in a discussion with Northwestern University student journalists.  Dr. Lund is a Senior Scientist and a bioinformatician at ACGT, Inc.  He completed his Ph.D. at Johns Hopkins University and his postdoctoral studies at Stanford University.  Prior to joining ACGT, Inc., Dr. Lund was an Assistant Professor at the University of Kentucky in Lexington where he taught and researched lifespan genomics.

[about_box image=””]David Cook, Esq. is legal counsel at ACGT, Inc. Mr. Cook has served the Chicago bar as a continuing legal education instructor and a clinical guest lecturer at various law schools. As a litigator, he appeared numerous times before the U.S. Courts of Appeals for the 7th and the 10th Circuits and has filed pleadings before the U.S. Supreme Court. Mr. Cook is a graduate of DePaul University College of Law and the University of Illinois at Champaign-Urbana[/about_box]


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