Science Exchange Stories: Pat Corsino from Nuovo Biologics

April 29, 2014 | Posted by Tess Mayall in Small Biotech Stories |

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Our user Pat Corsino, a R&D Manager at Nuovo Biologics, is studying the mechanism of action behind their antiviral and oncology technologies. I spoke with him about life and efficiency at an early-stage biotech, check out his advice about being proactive at a small biotech!

Q: What does Nuovo Biologics do?

Pat: We’re a small biotech company. We’re working on novel antiviral and anti-cancer therapeutics.

Q: How often does Nuovo Biologics contract out experiments?

Pat: Quite a bit, we have several collaborators all over the country. They help us plan and perform experiments, because we have limited capabilities in house. Right now, we need to get experiments done quickly in order to get funding to expand our laboratory.

Many collaborators do experiments for us, but sometimes there are projects that we can’t do through our network. That’s where Science Exchange comes in handy, because there’s a wealth of different experiments on the site. Read the rest of this entry »

Reproducibility through peer review

April 16, 2014 | Posted by Guest in Reproducibility |

This week we are featuring a guest post on how peer review can improve reproducibility. Check out Aimee Whitcroft from Publons’ thoughts below.

There has been much talk over the last few years about the fact that most research, particularly in the medical fields, may not be reproducible – a stunning waste of time and resources.

At Publons, we’ve been following the crisis closely, and we at think improved peer review is a vital first step towards reproducibility in academic and scientific literature. Read the rest of this entry »

Cell Line Authentication and Reproducibility

April 10, 2014 | Posted by Tess Mayall in Lab Profiles |
Cell line authentication at DDC Medical.

Cell line authentication at DDC Medical.

Over a third of cell lines used for biomedical research are contaminated or misidentified resulting in wasted resources, unreliable data, and irreproducible results.1 As a result, many journals and funding agencies now require cell line authentication for their studies.

Earlier this week, I wrote about our user, Eric Hugo, who did cell line authentication on several human cell lines that he had created. The experiment gave him confidence that his cell lines had the expected XY profile, hadn’t been contaminated, and were completely unique – all crucial findings for any researcher creating new cell lines.

Until recently, it has only been possible to authenticate cell lines from humans. Excitingly, DDC Medical has just developed and released a mouse cell line authentication test, providing researchers a way to validate their mouse cell lines for the first time. Read the rest of this entry »

Science Exchange Stories: Eric Hugo, adipose tissue researcher

April 7, 2014 | Posted by Tess Mayall in Stories |

erichugoWho knew fat could be so interesting? Eric Hugo did. Eric is an adipose tissue researcher at the University of Cincinnati. His research on adipose cells spans the cellular biology world. From breast cancer to antipsychotic drugs, Eric studies how dopamine receptors on adipose tissue cells respond to things in the body.

I spoke with Eric recently about his research, its implications, and how he used Science Exchange. Read his story below:

Q: How long have you been doing research?

Eric: I got my PhD in 1992, but I’ve only been in adipose biology since 2002. I had been teaching for ten years and in 2002 I decided to return to research. So, I started a second post-doc ten years after my first. The person that hired me gave me a second chance, and I found that I really enjoyed being back in the lab. It’s worked out; I’m very proud of the twenty publications I’ve received. Read the rest of this entry »

Science Exchange Stories: Eli Skipp, science meets art

April 2, 2014 | Posted by Tess Mayall in Stories |

Eli Skipp is one of the most unique users we’ve had. She is an artist who finds fun and interesting ways to integrate technology and science into her art. She successfully used Kickstarter to raise money to get her brother’s RNA sequenced using Science Exchange. Now she is loom weaving the sequence into a colorful, physical representation of her brother’s bases.

I talked to her recently about her insight into art and science. Check out her original Kickstarter video and read about her unique perspective on art and science below!

Read the rest of this entry »

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