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Quick Biology Q&A – Provider Spotlight

Guru Singh, Director of Scientific Content of Science Exchange, recently spoke with a member of Quick Biology. Follow the interview below.

Give us a quick overview of your company.

Quick Biology Inc. is a genomics startup in Pasadena, CA. We focus on developing new technologies provided to researchers, scientists, and physicians so that they may gain insightful and expedited results from their work. We offer a Next-Generation Sequencing (NGS) service as well as related reagents to investigate the functions of identified variants. We also help physicians to unlock the potential of NGS in disease diagnosis.

What accomplishments make Quick Biology Inc. stand out amongst its competitors?

We are one of the first sequencing providers to offer an optimized ATAC-seq service for many cell types, and it provides genome-wide profiles of open and accessible regions of chromatin that are indicative of active regulatory regions.

How do you define the ATAC-seq technique?

ATAC-seq is a sensitive technique used to rapidly assess genome-wide chromatin accessibility with fewer than 100,000 cells. When it is combined with NGS technology, we can obtain accurate results on chromatin accessibility at single-nucleotide resolution.

How does ATAC-seq stack up compared to traditional methods?

There are three major advantages of ATAC-seq over existing methods. After library preparation, the DNA is sequenced with NGS technology. As a result, we can obtain accurate results on chromatin accessibility at single-nucleotide resolution. ATAC-seq requires no sonication or phenol-chloroform extraction like FAIRE-seq, no antibodies like ChIP-seq and no sensitive enzymatic digestion like MNase-seq or DNase-seq. Unlike similar methods, which can take up to four days to complete, ATAC-seq preparation can be completed in under three hours so we can provide a quicker turnaround time for our clients. Another clear advantage is the low biological sample requirements. To illustrate, only 50,000 cells are sufficient for ATAC-seq, as opposed to other methods like ChIP-seq, MNase-seq, or DNase-seq that require at least 1,000-fold more material.

Tell us about your client base and where are they based.

Since our NGS service launched back in January 2016, we have served many clients from universities, hospitals and pharmaceutical companies with NGS projects (RNA-seq, ATAC-seq, ChIP-seq, WGS, and WES, etc.) from all over the world. Some of our major clients include Boston Biomedical, Cedars-Sinai Medical Center, Cold Spring Harbor Laboratory, NIH, VA medical center, Harvard University, Stanford University, USC, and UCLA, etc.

Can you tell our readers what makes your company competitive in this crowded genomics space?

We are equipped in-house with the latest technologies including Illumina NovaSeq 6000, HiSeq X Ten, HiSeq 4000, NextSeq500, MiSeq and Ion Proton instrumentation. Other factors that gives us an edge are our fast turnaround time and our competitive prices. We offer advanced bioinformatics analysis, including analysis for RNA splicing/RNA editing, and high-quality pictures to our clients for publication purposes.

You’ve made it apparent that Quick Biology Inc. has positioned itself as a leader in the genome sequencing field. What role has Science Exchange played in all of this? Has it made a positive impact on your company?

Since the launch of our NGS service on Science Exchange, we’ve had great experiences working with them. Science Exchange is an integral part of our sales and marketing strategies; it gives us exposure to a global scientific community, allows us to build an online reputation, and enables us to attract potential clients quickly. All of these benefits help Quick Biology Inc. to generate more revenue without exhausting our resources.

Science Exchange’s Sourcing Team is the secret ingredient to their successful business model. They are accommodating in mediating conversations or resolving problems with the client promptly.


Gursatya "Guru" Singh

Director of Scientific Content & Marketing

Gursatya Singh, also known as "Guru", manages the development and execution of strategic marketing initiatives to improve platform providers’ visibility and user experience. He is a true guru when it comes to helping providers better advertise their research services and providing buyers with easy access to recently commercialized external innovations. Whether working as a lab researcher, publishing scientific papers, or helping start life science startups, Guru believes in making the scientific world more collaborative and connected. Guru holds a master’s degree in biotechnology from the University of Delaware. Follow him on Twitter @Gursatya.

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