Science Exchange Scientist Trains Minority STEM Students

July 7, 2017 | Posted by Team in Conferences, Science Exchange News |

We are proud of our own Dr. Gabriel Roybal-Jungemann, Senior Scientist and R&D Specialist at Science Exchange, who will be speaking this week at a career panel aimed at increasing STEM leaders of color. Promoting diversity in science is crucial to achieving Science Exchange’s mission of enabling breakthrough research.

Gabriel joined Science Exchange after 12+ years in biomedical research and teaching at minority-serving institutions. He is also an entrepreneur, having founded his first company in 2013 to help improve family health and address health disparities.

As a scientist of color, Gabriel will be speaking to minority STEM students about entrepreneurship and to encourage alternative careers and innovation.

Read more about the event below!

Gabriel Roybal-Jungemann


This week, a select cohort of underrepresented minority STEM students will begin their path to leadership. Science Exchange will be represented with the participation of Dr. Gabriel Roybal-Jungemann, Senior Scientist, Research and Development Specialist, as a Career Panel Speaker for the inaugural SACNAS Chapter Leadership Institute (CLI).

The CLI is led by Society for Advancement of Chicanos/Hispanics & Native Americans in Science (SACNAS) and funded by the Genentech Foundation. Dr. Roybal-Jungemann has been involved with SACNAS since 2005.

The institute, held July 7 – 8 at San Jose City College, is two full days of small group exercises, keynote speakers, leadership development workshops, networking opportunities, and extensive community building among selected participants from colleges and universities across California.

SACNAS Director of Programs, Mr. Rolando Madrid says the Genentech Foundation is the ideal partner to nurture a new generation of leaders. He notes, “We are proud to partner with the Genentech Foundation to launch our inaugural Chapter Leadership Institute. Genentech understands the importance of investing in our next generation of underrepresented minority scientists and is doing their part to ensure that the future is well developed and prepared to tackle the issues of the 21st century.”

Participants of the CLI are all part of the SACNAS chapter program, a national network of 115 student and professional chapters that work to strengthen community and peer support for minority scientists at the local and regional levels.

Ms. Tanya Beat, manager of the SACNAS Chapter Program, says, “The CLI will equip students with critical take-away tools including individual leadership plans, mentor-mentee relationships, and a rich network of peers and STEM leaders from California.”

Since 2009, SACNAS leadership initiatives have trained a cohort of 30 PhD-level scientists each year, making it the largest group of emerging STEM leaders of color in the country. With the introduction of CLI, SACNAS is expanding leadership training to the undergraduate and graduate student levels, nurturing leaders earlier in their educational and career trajectories.

View the entire SACNAS Chapter Leadership Institute Cohort.

 

About SACNAS & The Genentech Foundation

SACNAS is an inclusive organization dedicated to fostering the success of Chicanos/Hispanics and Native Americans, from college students to professionals, in attaining advanced degrees, careers, and positions of leadership in STEM. Considered the founder of the biotechnology industry, Genentech is leader in the discovery, development, manufacturing, and commercialization of medicines that treat patients with serious or life-threatening medical conditions. The Genentech Foundation focuses on three charitable giving goals: advancing scientific knowledge, enhancing health outcomes, and building strong communities to build real and lasting change.

 

Science Exchange enables completion of the Kakapo 125 Project

July 5, 2017 | Posted by Team in New Innovations, Research, Science Exchange News |

Sequencing the genomes of every individual kākāpō in the entire species

Kakapo bird

The kākāpō is a species of large, flightless, nocturnal, ground-dwelling parrot of the super-family Strigopoidea endemic to New Zealand. With only 154 living individuals remaining, it’s one of the world’s rarest birds.

Genetic Rescue Foundation

Since early 2016, The Genetic Rescue Foundation, in partnership with The Department of Conservation (DOC), The University of Otago, Duke University, New Zealand Genomics Ltd (NZGL), Te Rūnanga o Ngāi Tahu, and Science Exchange, has funded and managed the effort to sequence the genomes of every individual in this quirky, critically endangered species.

DNA Portraits

The Genetic Rescue Foundation’s fundraising has come in the form of generous private donations, kākāpō DNA portrait sales and a successful crowdfunding campaign on Experiment.com.

To date, the project has successfully sequenced 80 kākāpō. Part of the work was made possible by collaborating with DNA sequencing service providers on the Science Exchange network of 2,500+ service providers. Today we’re thrilled to announce that Science Exchange will be funding the remainder of the project in order to bring it to completion!

Kinghorn Centre and Garvan Institute Logos

The remaining sequencing will be performed by The Kinghorn Centre for Clinical Genomics at The Garvan Institute of Medical Research in Sydney, Australia. The Kinghorn Centre is a frequently used provider of DNA sequencing services on the Science Exchange network.

Detailed genetic data for every individual in an entire species is a world first and represents a genomics-focused paradigm shift in modern conservation efforts. The possible discoveries that will come from this rich dataset are limitless. Scientists’ immediate efforts will be focused on finding genetic links to dwarfism, infertility and other diseases and conditions hampering kākāpō population recovery.

The dataset will be controlled by the New Zealand government but will be made available for all non-profit researchers to use. All sequencing will be completed by the end of 2017, with the full dataset available for researchers in 2018.

“Science Exchange has made completing this project possible. They’ve achieved that by providing The Genetic Rescue Foundation with unrivaled access to the world’s best scientific service providers and by stepping in to fund the remainder of the project. This data will steer kākāpō conservation decisions for years and decades to come. It may prove to be the deciding factor in saving this species.”

David Iorns

David Iorns – Founder of The Genetic Rescue Foundation

Science Exchange is proud to be involved with this pioneering conservation initiative. Join Science Exchange today and work with us to accelerate your research.

Science Exchange Raises $28M in Series C Funding

June 29, 2017 | Posted by Team in Company, Press Release, Science Exchange News |
Science Exchange Team

The Science Exchange Team

Funding led by Norwest Venture Partners with participation from Union Square Ventures, Maverick Capital and Collaborative Fund

Palo Alto, CA – June 29, 2017 As further evidence of its position as the world’s leading platform for outsourced research and development (R&D), Science Exchange today announced it has raised $28 million in Series C funding. Founded in response to the global growth in outsourced R&D services, the company has raised more than $58 million since its inception in 2011. Norwest Venture Partners led the latest round with participation from existing investors Union Square Ventures, Maverick Capital, and Collaborative Fund.

“In the last decade, outsourcing of R&D has become a core strategy for improving efficiency and providing access to innovation for top companies globally. Forty percent of R&D spend is now outsourced and this trend continues to grow,” explained Science Exchange CEO Elizabeth Iorns, Ph.D., a research scientist who co-founded the company. “At the same time, businesses are challenged to manage their outsourced R&D. They need to track progress and provider performance across what could be hundreds of service provider relationships, impacting the cost, quality and timeliness of research projects. The Science Exchange platform solves this by removing barriers in the outsourcing process – providing companies with instant access to a network of pre-qualified service providers, as well as contracting, project management and reporting tools.”

As part of the Series C, Casper de Clercq, General Partner at Norwest and veteran of the life sciences industry with more than 20 years of commercialization and operating experience, will join the company’s board.

“Science Exchange has developed an outsourcing platform that is enjoying tremendous momentum as many of the world’s largest pharma and biotech companies have signed up,” said Casper de Clercq, General Partner at Norwest. “They are well-positioned as the leader in a large and expanding market. We are excited to help Science Exchange become the world’s largest platform for outsourced R&D.”

“We’re thrilled to be partnering with such prestigious investors to help us grow our business at such a critical time in the evolution of R&D outsourcing,” commented Iorns. “This investor confidence confirms our business strategy and potential for continued growth.”

Through the Science Exchange platform, researchers have easy and secure access to more than 2,500 of the world’s premier outsourced R&D service providers — qualified contract research organizations (CROs), contract manufacturers (CMOs), academic labs, and government facilities. Thousands of scientists have used the platform to support their pursuit of breakthrough scientific discoveries, including those from 10 of the top 20 biopharma companies. In fact, the company has grown its enterprise-wide strategic sourcing agreements with leading pharmaceutical companies by more than 2,000 percent since 2015.

Science Exchange plans to use the funding to continue its expansion beyond biopharma into other industries where scientists are faced with R&D outsourcing challenges – including agricultural science, cosmetics, aerospace and industrial chemicals. The company will strategically hire across product, engineering, sales, marketing, and customer success.

About Science Exchange
Science Exchange is the world’s leading platform for outsourced research, providing an efficient procure-to-pay platform for ordering services from a network of more than 2,500 qualified scientific service providers, all with pre-established contracts in place that protect client intellectual property and confidentiality. The platform increases scientists’ access to innovation and improves productivity, freeing them up from the administrative tasks and delays associated with sourcing, establishing and managing service provider contracts. Additionally, the Science Exchange enterprise program enables organizations to consolidate research R&D outsourcing spend into a single strategic relationship, driving efficiency and cost savings. Since being founded in 2011, Science Exchange has raised more than $58 million from Norwest Venture Partners, Maverick Capital Ventures, Union Square Ventures, Collaborative Fund, Index Ventures, OATV, the YC Continuity Fund, and others. For more information, visit http://www.scienceexchange.com. Follow the company on Twitter @ScienceExchange.

About Norwest Venture Partners

Norwest Venture Partners is a leading Silicon-Valley based venture capital and growth equity investment firm managing more than $6 billion in capital. Since our inception, we have invested in more than 600 companies. The firm invests in early to late stage companies across a wide range of sectors with a focus on consumer, enterprise, and healthcare. We offer a deep network of connections, operating experience, and a wide range of impactful services to help CEOs and founders advance on their journey. Norwest has offices in Palo Alto and San Francisco, with subsidiaries in Mumbai and Bengaluru, India and Herzelia, Israel. For more information, please visit http://www.nvp.com. Follow Norwest on Twitter @NorwestVP.

# # #

Media Contacts

Kerry Metzdorf
Representing Science Exchange
kerry@big-swing.com
978-463-2575

Ellie Javadi
Norwest Venture Partners
ejavadi@nvp.com
650-289-2227

 

Covance Nonclinical Services Now Listed On Science Exchange

June 14, 2017 | Posted by Team in Company, Drug Discovery, Science Exchange News, Uncategorized |

Covance   +  Science Exchange

 

Biopharma scientists seeking to outsource nonclinical studies have a new way to access the scientific expertise of Covance, a market leader in drug development. Covance’s nonclinical scientific services – including lead optimization, safety assessment, drug metabolism and bioanalytical solutions – are now available through Science Exchange. Scientists can order available study services from Covance by visiting the Covance Storefront on ScienceExchange.com. Or they can contact the Science Exchange Concierge Service to have a Sourcing Manager prepare custom quotes and provide start-to-finish project management.

Scientists from around the world already use Science Exchange to save time and money by ordering services from our network of more than 6400 pre-qualified service providers. With Covance joining the Science Exchange network, scientists can further benefit by being able to easily access the deep nonclinical scientific expertise of one of the world’s top CROs through the convenience of the Science Exchange platform. 

In addition, researchers at companies who have established enterprise-level Master Service Agreements (MSAs) with Science Exchange can get projects started with Covance almost instantly.

As an introductory offer, through September 30, 2017, requesters can take advantage of special fast study starts on select GLP Toxicology in vivo studies or full IND/CTA-enabling packages available from Covance, ordered through the Science Exchange platform.  

Request a quote today — access nonclinical scientific services from Covance through the Covance Storefront on Science Exchange.

 

* To be eligible for introductory offer, work must begin by September 30, 2017. Additional terms and conditions apply.  This is a limited time, limited capacity offer – Covance reserves the right to end these promotions at any time, without notice.

Alzheimer’s Drug Discovery Foundation and Science Exchange Launch ADDF ACCESS

June 9, 2017 | Posted by Team in Company, Drug Discovery, New Feature, Press Release, Research, Science Exchange News |

New “CRO Finder” Connects Scientists with Specialized Resources

by Cliff Culver, VP Strategy and GM, Science Exchange | www.scienceexchange.com

NEW YORK, June 7, 2017 — The Alzheimer’s Drug Discovery Foundation (ADDF), the only public charity solely focused on funding the development of drugs for Alzheimer’s, and Science Exchange today announced the launch of ADDF ACCESS, a first-of-its-kind online platform designed to match scientists working on central nervous system (CNS) diseases with a vetted network of contract research organizations (CROs).

ADDF ACCESS meets the unique needs of scientists in both academia and small biotech companies by combining the resources of Science Exchange, the world’s leading marketplace for outsourced research and development, with the Alzheimer’s drug discovery knowledge of the ADDF.

“Drug discovery requires a wide range of expertise, from medicinal chemistry and pharmacology to project management and regulatory affairs,” said Lauren Friedman, Ph.D., ADDF ACCESS program director. “Researchers don’t always have the interdisciplinary teams needed to develop a drug. We created the new ACCESS website with Science Exchange to connect researchers with high-quality CROs and provide guidance and resources to help successfully advance their drug programs.”

On ADDF ACCESS, scientists will find:

A network of CROs and consultants with CNS drug discovery expertise, vetted by the ADDF and Science Exchange
An expert concierge service to match scientists with the right CROs, solicit multiple competitive quotes, and manage projects
A library of educational resources, including a guide to CNS drug discovery and development
“Early-stage drug research is the engine that drives progress in treating Alzheimer’s and CNS diseases,” said Dr. Howard Fillit, M.D., executive director and chief science officer of the ADDF. “We are excited to provide a resource specifically designed to facilitate connections that fuel this engine. Every scientific discovery gets us closer to finding a treatment.”

“Eliminating the laborious, resource-intensive process of finding and negotiating with CROs and other service providers helps researchers focus on their important work, and that’s what Science Exchange is all about,” said Elizabeth Iorns, Ph.D., CEO and co-founder of Science Exchange. “We are thrilled to partner with the ADDF on this new ACCESS website that will give scientists specializing in CNS diseases the tools and services they need to bring important, potentially life-saving drugs to market faster.”

To learn more, visit https://www.alzdiscovery.org/addf-access

About the Alzheimer’s Drug Discovery Foundation (ADDF)
Founded in 1998 by Leonard A. and Ronald S. Lauder, the Alzheimer’s Drug Discovery Foundation (ADDF) is dedicated to rapidly accelerating the discovery of drugs to prevent, treat and cure Alzheimer’s disease. The ADDF is the only public charity solely focused on funding the development of drugs for Alzheimer’s, employing a venture philanthropy model to support research in academia and the biotech industry. Through the generosity of its donors, the ADDF has awarded over $100 million to fund more than 500 Alzheimer’s drug discovery programs and clinical trials in 18 countries. To learn more, please visit: http://www.alzdiscovery.org/.

About Science Exchange
Science Exchange is the world’s leading marketplace for outsourced research. Science Exchange provides an efficient procure-to-pay platform for ordering services from the world’s largest network of scientific service providers. Through Science Exchange, clients gain access to over 2,400 qualified service providers, all with pre-established contracts in place that protect client intellectual property and confidentiality. This increases scientists access to innovation and significantly improves their productivity because they are freed up from the administrative tasks and delays associated with sourcing, establishing and managing service provider contracts. At an organizational level, the Science Exchange enterprise program enables organizations to consolidate the long tail of research outsourcing spend into a single strategic relationship driving significant efficiency and cost savings. To date, Science Exchange has raised over $30 million from Maverick Capital Ventures, Union Square Ventures, Index Ventures, OATV, the YC Continuity Fund, and others. For more information, visit www.scienceexchange.com.

SOURCE Alzheimer’s Drug Discovery Foundation

Related Links

http://www.alzdiscovery.org

Shark Poaching Exposed by the Science Exchange Network

June 8, 2017 | Posted by Team in Research, Stories |

by Kaitlin Ziemer and JR Clark, Science Exchange | www.scienceexchange.com

Today, we celebrate World Oceans Day with a Science Exchange success story. This is a story about connecting ocean conservation advocates with the scientists whose expertise is helping to guide conservation strategy.  

World Oceans Day -- Sharks

Robust shark populations are a sign of healthy oceans. [photo credit: JR Clark]

The Project Earth team from Fusion TV approached Science Exchange with a unique sequencing project. They were working on a documentary film about the illegal poaching of sharks for use in shark cartilage capsules.

Studies have shown that shark cartilage is ineffective or even pro-inflammatory. Despite this and the importance of conserving sharks, who are the ocean’s apex predators, the cartilage capsule industry has managed to persuade retailers and consumers that shark cartilage could promote joint and bone health.

The Fusion TV Project Earth team wanted to find out if cartilage pills contained illegally obtained shark tissue. They needed a service provider who could perform DNA sequencing on 30 different supplements to see if they contained protected or endangered sharks.

Through the Science Exchange network, the Fusion TV Project Earth team obtained sequencing services from Laragen, Inc., a California-based service provider. Together, they were able to detect DNA from the endangered scalloped hammerhead sharks, whose trade is highly regulated, in the capsules sold at nationwide health food stores and pharmacies.

The Fusion TV Project Earth team urged both the cartilage pill manufacturers and retailers to share more precise information about the origins of the shark material found in the pills. In response, two major retailers removed shark cartilage pills from their stores and website.

These results showed that scientific evidence can influence positive change and help to protect our natural environment. And by providing the Fusion TV Project Earth team with easy access to the world’s best scientific service providers, Science Exchange helped put the data directly into the hands of the agents of change.

About the authors:

 

Kaitlin Ziemer, B.S., is a Senior Sourcing Manager and Account Lead at Science Exchange. With her extensive prior experience in managing toxicology and regulated studies for large biopharma and contract research organizations, Kaitlin now specializes in human and animal tissue procurement.

JR Clark, M.S., is Science Exchange’s expert in shark biology, given his extensive research experience in evolutionary development and reproductive behavior of vertebrates. As a Sourcing Manager, he manages a wide variety of projects from basic research through drug discovery.

New Feature for Requesters: Add Collaborators to Your Order

June 1, 2017 | Posted by Team in Company, New Feature, Science Exchange News |

by Elizabeth Iorns, Co-Founder & CEO, Science Exchange

Science, by its very nature, lends itself to collaboration. At Science Exchange, we endeavor to make discovery and access to scientific services as easy as possible – while also improving researchers’ ability to collaborate effectively.

With that goal in mind, we have released the Requester Collaboration feature. This feature allows requesters of scientific services to invite and manage additional collaborators for a project.

Examples of collaborators include:

  • A member of your organization’s accounting team who needs to view the project to make payment.
  • A colleague helping you to work through the project details with the service provider.
  • An administrator seeking a high level overview of research activities of their organization on Science Exchange.

The new feature will enable:

  • Intuitive addition of collaborators to existing projects
  • Transparent communication between collaborating requesters and the service provider
  • Easy transfer of ownership between requesters/collaborators

We will continue to listen to our users and bring new features to our platform to facilitate scientific discovery. To learn more about the Requester Collaboration Feature, view our video demo or check out the Q&A below. If you’d like a personal demo of this feature or the Science Exchange marketplace, submit a request here.

Requester Collaboration Feature Video Demo

 

Requester Collaboration Feature Q&A

What can collaborators do?

Invited collaborators will see the order on their Science Exchange Dashboard. The collaborator can access the order page, post messages, accept quotes, and mark orders as completed.

How will collaborators be notified?

Collaborators will get email notifications regarding new messages that have been posted to the order page. They can also reply to the new message email notification from their inbox and the response will be posted to the order page. However, they will not get email notifications when the provider generates a quote for the request or that the order has been completed.

How does this change what the primary Requester can do?

There are no changes for the primary Requesters — they can still do everything, e.g., post messages, accept quotes, and mark orders as completed. As the primary Requester, you will also be notified via email of main updates regarding the order, e.g., messages, quotes submitted, quotes accepted, provider completing the order. However, you can transfer the ownership of the order to a collaborator so that they become to primary Requester.

How do I invite a collaborator?

  1. Go to the order page
  2. On the right-hand side, under “Researchers,” you’ll see a link called “Manage.” Click on that link.
  3. Enter your collaborator’s email and then invite them.
  4. The collaborator will get an email from Science Exchange with the invitation. They should click on the green button in the email.
  5. The collaborator will (sign up for a Science Exchange account, and then) arrive at the order page.
  6. Collaborator can post messages, accept quote, mark order as complete.

How do I transfer ownership of the order to my collaborator?

  1. Go to the order page
  2. On the right-hand side, under “Researchers,” you’ll see a link called “Manage.” Click on that link.
  3. You’ll see your collaborator’s name. Click on the blue “Make Owner” link.

Still have questions?

We’re happy to help! Contact us here with your questions.

Navigating the Fragmented Outsourced Manufacturing Sector

May 30, 2017 | Posted by Team in New Innovations, Outsourcing Best Practices, Research, Uncategorized |

Contract manufacturing of pharmaceuticals is growing rapidly and has recently seen an uptick in merger and acquisition activity, such as Thermo Fisher’s bid to acquire Patheon.  Despite the consolidation, outsourced pharmaceutical manufacturing remains a fragmented market, as outlined in a recent report and summary. Discovering and qualifying outsourced service providers is already challenging, and the persistent fragmentation compounds the challenges.

Science Exchange has a unique vantage point for evaluating contract manufacturing services based on our diverse client base and the associated customer experience scorecard data we gather. In this post, we share our insights around navigating the complex contract manufacturing sector.

Demand for contract manufacturing services

The high demand for external manufacturing capacity and expertise is one driving force behind the proliferation of CMOs and CDMOs. According to a 2016 survey, biopharma organizations cite the need to improve quality as the primary reason for using contract manufacturing organizations (CMOs) and contract development and manufacturing organizations (CDMOs). Additional goals for outsourcing include reducing time to market, controlling costs, achieving supply chain diversity, leveraging regulatory expertise, and accessing specialized technologies, including those required for complex biologics manufacturing processes.

Competition between CMOs: Innovative manufacturing services

Competition in the marketplace is driving CMOs to develop innovative manufacturing technologies to capture new service categories — choosing a cutting-edge CMO partner can give a biopharma company advantages over its competitors.

Many CMOs and CDMOs have adopted process improvements to provide their clients with faster cycle times and more informed decision-making. These improvements include cloud-based computing, real-time risk-monitoring tools, and integrated quality-by-design during process development. Such process improvements are especially important given the ability of multiple CMOs to manufacture the same API. Nearly 90% of the volume of drugs sold are generic small molecule therapeutics, requiring high production capacity that may be provided by any number of CMOs.

Other CMOs differentiate themselves through specialized expertise – for example, they may be leaders in developing novel formulations, such as nanoparticles or lipid-based delivery systems. Some CMOs offer specialized regulatory certifications, such as CLIA/CAP, GLP, and GCP. Although cGMP compliance is not absolutely required for all CMOs, most reputable CMOs are cGMP certified.

Contract manufacturing of biologics and complex therapeutics: a growth opportunity

It has been challenging to outsource the manufacture of biologics, such as vaccines, therapeutic monoclonal antibodies, and cell therapies, and non-biological complex drugs. These fast-growing segments are faced with regulatory hurdles, a need for specialized drug delivery devices, and inherent risks involved in method transfer and ensuring consistent supply.

Despite the challenges of method transfer, technological improvements are facilitating partnerships between biopharma companies and CMOs in biologics pipelines. Emerging categories of therapeutics, such as cell therapies and antibody-drug conjugates, as well as novel formulations, such as nanoparticles, have benefited from specialized manufacturers. Even though some of these specialty drug products may require bespoke manufacturing processes, CMOs stay agile through integrated quality-by-design during process development and take advantage of connected single-use technologies for streamlined yet flexible bioprocessing.

Barriers facing discovery and qualification of manufacturing service providers

The demand for contract manufacturing, combined with the growth opportunities around innovation and biologics, have resulted in a marketplace with thousands of active CMOs and CDMOs. It can be time-consuming and difficult to identify qualified service providers with the right certifications to meet regulatory compliance requirements. Though many service providers are staffed by innovative, highly qualified scientists with experience in the biopharma industry, many service providers lack such expertise.

Because there are no clear third-party qualification processes or objective benchmarks for quality, and because biopharma companies lack the time to perform regulatory compliance audits of all the service providers in this fragmented sector, over 68% of biopharma companies use a preferred provider strategy for outsourced manufacturing. Relying on preferred providers may decrease the agility of companies to take advantage of emerging technologies.

For contract manufacturing to add maximum value to an organization, responsible teams should consider adhering to a defined sourcing strategy.

Checklist for a successful contract manufacturing partnership

To maximize the advantages offered by a successful CMO partnership, the procurement and external resource management teams of a biopharma company must ensure that their sourcing strategy includes:

  • Keeping abreast of emerging technologies and service providers;
  • Stringently qualifying service providers based on turnaround time, product quality, cost, and regulatory compliance;
  • Identifying service gaps and assessing value of existing preferred providers;
  • Streamlining the contracting process to enable rapid onboarding of innovative service providers;
  • Establishing contracts that protect intellectual property and confidentiality, to maintain competitive advantage and minimize risk;
  • Managing project milestones to ensure that projects are completed on time and as planned;
  • Keeping meticulous records so that methods can be transferred in house or to other service providers as needed.

Science Exchange  streamlines management of strategic manufacturing partnerships

Science Exchange, the largest marketplace for outsourced scientific services, enables biopharma companies to rapidly find and order cutting-edge technologies and services from a proprietary network of 2500+ qualified service providers, including many providers of contract manufacturing services.

Science Exchange’s Provider Management Team continually seeks to build its network by adding high-quality, innovative service providers with cutting-edge expertise in emerging manufacturing technologies.

Science Exchange’s dedicated staff scientists on our Sourcing Team help biopharma manufacturing teams find the best service provider for each scope of work, obtain multiple competitive quotes, and provide end-to-end project management. By using Science Exchange, manufacturing teams save hours or days per project that they would otherwise spend identifying providers, obtaining quotes, and managing projects.

Science Exchange mitigates inherent risks of outsourced manufacturing; all service providers on the platform are pre-qualified through a stringent vetting process and provides information on past performance, using an ISO 9001 Quality Systems-certified process.

Manufacturing scientists at top biopharma companies are already using Science Exchange to access hundreds of qualified specialty providers. The platform is enabling these scientists to order services from known and new manufacturing service providers, such as ImQuest, Almac Sciences, Recipharm, ChemPartner, Synovel Laboratory, Bioneer A/S, Solvias AG, WuXi AppTec, Lonza, and Piramal.

Contact Science Exchange today to discuss your manufacturing needs.

Kakapo 125 – Second 40 kākāpō sequenced

April 11, 2017 | Posted by Team in Science Exchange News |

Kakapo - Trevor

Science Exchange is a collaborator in the Kakapo 125 Project. The objective of this project is to sequence the genomes of all known living kākāpō. We’re pleased to share an update on the project’s progress. NZGL has completed sequencing the second 40 individual kākāpō!

The project is now past the halfway point with approximately 70 individuals remaining before we’ve successfully sequenced every individual in the entire species.

In the News

Scientific American Kakapo

The Kakapo 125 Project has been receiving worldwide media coverage. Here’s a selection of articles published about this groundbreaking work.

Sponsorship

Portraits

Sponsors of individual kākāpō genomes will shortly be receiving their custom DNA artwork. Each DNA portrait is constructed from the genetic data of the individual kākāpō and is guaranteed to be unique. Genome sponsorship forms a key component of ongoing fundraising for the project as we strive to sequence every genome in an entire species.

sponsor a genome button


Science Exchange is proud to be involved with this pioneering conservation initiative. Join Science Exchange today and work with us to accelerate your research.

Service Providers Aim for Cancer Moonshot at AACR 2017

April 7, 2017 | Posted by Diana Truong in Conferences, Drug Discovery, Events, Helpful products, New Innovations, Research |

Greetings from the AACR Annual Meeting!

This year, we heard Joe Biden’s report on the progress of the Beau Biden Cancer Moonshot Initiative, compared immuno-oncology combination therapies, and mulled over the use of CRISPR screening to finding epigenetically controlled loci.

Joe Biden delivers the Cancer Moonshot Initiative update at AACR 2017

We also checked out the groundbreaking research being done by service providers on the Science Exchange network. Their work directly addresses the recommendations made last fall by the Moonshot’s Blue Ribbon Panel, and we are excited to give cancer researchers rapid access to these technologies through the Science Exchange platform!

Here are a few highlights from our exploration of #AACR17:

First humanized mouse model of tumor growth in bone: Pharmatest and Taconic Biosciences

The Moonshot Initiative’s recommendations specifically called out the potential of humanized mouse models to recapitulate the cellular architecture and heterogeneity found in human tumors. Traditional preclinical models that lack functional interactions between tumor, immune system and microenvironment have not been effective at predicting safety and efficacy of immunomodulating cancer drugs.

Taconic Biosciences showcases its novel animal models at AACR 2017

Pharmatest Services, Ltd. and Taconic Biosciences, both leaders in the development of predictive animal models, presented a poster at AACR 2017 showing the proliferation of human breast cancer cells in the bone injection site of humanized mice. The observed tumor growth, bone remodeling, and infiltration by human immune cells were similar to that seen in human breast cancer patients suffering from bone metastases.

Validation of this mouse model would be a very promising development for preclinical testing of immuno-oncology drug candidates and combination therapies.

 

Mass spectrometry imaging to characterize tumor microenvironment: Imabiotech

Imabiotech’s novel mass spectrometry imaging technology provides better toxicity and efficacy assessments in a number of therapeutic research areas, including immuno-oncology.

One challenge facing the Cancer Moonshot Initiative is that novel technologies are required to address tumor heterogeneity (at the cellular and molecular levels). Thus, the Blue Ribbon Panel called out multiplexed, quantitative imaging as a promising way to connect function with localization.

Imabiotech Corporation is a widely-published expert in the emerging field of mass spectrometry imaging, which is a promising technology to address tumor heterogeneity. Their poster and exhibit at AACR 2017 showcased how mass spectrometry imaging could be used to quantitatively characterize responses to immunotherapy in the tumor microenvironment, with spatial resolution.


Toward 3D patient-derived models of breast cancer, lung cancer, and glioblastoma: KIYATEC, Inc.

Another of the most challenging aspects of oncology is the fact that each patient has a different response to a particular therapy. Recognizing this, the Moonshot Initiative’s recommendations included a call to establish patient-derived test models, such as organoids and xenografts, in which candidate drugs could be tested before treatment.

KIYATEC presents 3D cell-based models for drug response profiling at AACR 2017

KIYATEC, whose expertise lies in generating and using 3D cell-based models for drug response profiling, presented their work on breast cancer, lung cancer, and glioblastoma multiforme (GBM), in three posters at AACR 2017.

One study addressed the challenges facing small cell lung cancer (SCLC) patients, for whom surgical resection is rarely feasible. Therefore, patient-derived tissue is difficult to obtain. KIYATEC was able to isolate functional cancer stem cells and circulating tumor cells, label-free, from SCLC patients, with the aim of developing 3D microtumors from these cells.

KIYATEC also showed that 3D models of breast cancer, which incorporated multiple stromal cell types and immune cells, responded differently to immune checkpoint inhibitors than standard 2D cell culture models. Finally, KIYATEC tackled GBM, for which therapy is particularly confounded by intra-tumor and inter-patient heterogeneity. They developed an efficient method to develop patient-derived 3D models, which may enable more personalized treatments for GBM.

Interested in working with these service providers? Order services on Science Exchange today, or contact us about your project.

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