On-Demand Webinar: Complex, 3D Screening for Cancer Immunotherapy

Screening for potential anti-cancer immunotherapies benefits from 3D platforms to detect complex, multi-cell and multi-step effects on the immune system. Watch this on-demand webinar to learn: Differences between 2D and 3D drug screening models How 3D cultures can mimic cancer cell-immune cell interactions How to maximize reproducibility in a 3D drug screening assay https://youtu.be/hyhvBeAyuLs   […]

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New Providers on Science Exchange: Predictive Models and Analytical Tools for Translational Research

translational-research

If you aren’t exploring the latest cell culture models of human tissue for nonclinical and preclinical testing, you should be. That’s the bottom line of today’s Science Exchange service provider roundup — three of the five newest service providers on our platform are experts in developing predictive models. Advances in predictive model systems Axiogenesis, based […]

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Mass Spec: Shedding Light on Cancer Biomarkers with Century-Old Technology

cancer

Imagine telling the inventor of the radio that the technology he discovered was now found in almost every kitchen in America, and that you used it to make your popcorn last night. He’d probably be surprised, and maybe you are, too.  Sound far-fetched? Many aspects of modern life rely on technology that was first identified […]

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Techniques Series: Next Generation Sequencing technologies

sequencing

  by  EMSL    This is a guest post by James Hadfield, Head of the Genomics Core Facility at Cancer Research UK. Today there are three main next-generation sequencing (NGS) technologies; Illumina, Ion Torrent and 454. Sanger sequencing is still used by almost all research labs and remains a key tool for simple clone verification or PCR […]

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Techniques Series: Using Flow Cytometry

flow-cytometry

  by  adpal3180    Flow Cytometry is a powerful technique that enables researchers to conduct a rapid and multi-parametric analysis of single cells simultaneously. Of late, it has become an indispensable tool in basic cell biology and medical research, immunological studies, drug discovery, and even diagnosis of diseases. The applications vary as well, from cell sorting of […]

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Techniques Series: Inductively Coupled Plasma (ICP)

plasma

This is the third in a series of posts on scientific techniques, and how to use them in your research Inductively Coupled Plasma (ICP), usually coupled with optical emission spectrometer (OES), atomic emission spectrometer (AES), or mass spectrometer (MS), has been most commonly used by environmental chemists to detect metals in soil or watershed, but it is […]

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Techniques Series: Using Confocal Microscopy

confocal-microscopy

  by  Carl Zeiss Microscopy    This is the second in a series of posts on scientific techniques, and how to use them in your research. Confocal microscopy is an essential tool in modern cell biology with a wide range of applications. It can be used to study cellular structures and subcellular components of organisms ranging from yeast to […]

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Techniques Series: Creating a Molecular Brain Map

molecular-brain-map

This is the first in a series of posts on scientific techniques, and how to use them in your research. The brain is comprised of billions of individual neurons. Cells in the brain are densely packed with intermixed, often overlapping types. An excitatory neuron for instance may be surrounded by dozens of inhibitory interneurons and glia. So […]

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