Cell Line Authentication and Reproducibility

April 10, 2014 | Posted by Tess Mayall in Lab Profiles |
Cell line authentication at DDC Medical.

Cell line authentication at DDC Medical.

Over a third of cell lines used for biomedical research are contaminated or misidentified resulting in wasted resources, unreliable data, and irreproducible results.1 As a result, many journals and funding agencies now require cell line authentication for their studies.

Earlier this week, I wrote about our user, Eric Hugo, who did cell line authentication on several human cell lines that he had created. The experiment gave him confidence that his cell lines had the expected XY profile, hadn’t been contaminated, and were completely unique – all crucial findings for any researcher creating new cell lines.

Until recently, it has only been possible to authenticate cell lines from humans. Excitingly, DDC Medical has just developed and released a mouse cell line authentication test, providing researchers a way to validate their mouse cell lines for the first time. Read the rest of this entry »

Science Exchange Stories: Eric Hugo, adipose tissue researcher

April 7, 2014 | Posted by Tess Mayall in Stories |

erichugoWho knew fat could be so interesting? Eric Hugo did. Eric is an adipose tissue researcher at the University of Cincinnati. His research on adipose cells spans the cellular biology world. From breast cancer to antipsychotic drugs, Eric studies how dopamine receptors on adipose tissue cells respond to things in the body.

I spoke with Eric recently about his research, its implications, and how he used Science Exchange. Read his story below:

Q: How long have you been doing research?

Eric: I got my PhD in 1992, but I’ve only been in adipose biology since 2002. I had been teaching for ten years and in 2002 I decided to return to research. So, I started a second post-doc ten years after my first. The person that hired me gave me a second chance, and I found that I really enjoyed being back in the lab. It’s worked out; I’m very proud of the twenty publications I’ve received. Read the rest of this entry »

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