Science Exchange providers featured in Cell article!

July 23, 2012 | Posted by Elizabeth in Provider Spotlight |

We are really excited to see Cell mention Science Exchange in it’s latest issue “Science for Sale: Academic Meets Industry”. It’s great to see Cell recognize how academic research is evolving and provide concrete examples of how innovative scientists can use marketplaces like Science Exchange to establish collaborations, access specialist expertise, and create unique funding opportunities for their own research.

In particular, we are thrilled that both scientists featured in the article are providers at Science Exchange! This means you can easily access their specialist expertise from their Science Exchange facility pages (info below): Read the rest of this entry »

How can core facilities better connect with the researchers who need them?

April 29, 2012 | Posted by Team in Outsourcing Trends |

The following article appeared in the “Solutions” section of the 2012 ABRF Communications magazine, distributed that the 2012 ABRF conference in Orlando, FL.  

A View from the Core

When Dr. Todd Waldman MD PhD, made his ground-breaking discovery into the genetic basis for glioblastoma multiforme (GBM) brain tumors, he did so through the help of core facilities. GBM is the most common and deadly form of primary brain tumor; it was infamously responsible for the death of Senator Edward Kennedy in 2009. Dr. Waldman’s molecular oncology group at Georgetown University discovered that multiple GBM cell lines have mutations in the STAG2 gene, which cause chromosomal instability during cell division. To explore the clinical relevance of his findings, Dr. Waldman turned to the Lombardi Cancer Center Histopathology and Tissue Shared Resource (HTSR). The HTSR stained multiple tissue microarrays containing primary GBM and Ewing’s carcinoma samples for STAG2, and confirmed that the protein was indeed missing in many primary tumors. These results were a critical component of the paper published by Waldman and colleagues in Science last year. (Learn more about how the HTSR helped Dr. Waldman and his colleagues here).

Projects like Dr. Waldman’s are at the heart of a core facility’s mission, namely to provide investigators with the specialized resources and expertise they need to produce the best possible scientific output. As a primary resource for human patient tissues and histopathology expertise, the core was able to give the study its translational focus, demonstrating the clinical significance of Dr. Waldman’s findings. HTSR has a highly skilled and experienced staff that handles approximately 2000 requests for services each year, providing a degree of expertise and professionalism that would be hard to match by an individual researcher attempting to build up the necessary techniques in their own lab.

And yet, core facilities often remain under-utilized. HTSR Co-Director Dr. Deborah Berry PhD realized that despite internal demand, there were times when the facility was not as busy as it could have been. In short, they had excess capacity that they could be using to fuel translational research beyond the borders of their institute.  Dr. Berry realized that researchers from other institutes could greatly benefit from the resources and expertise she and her colleagues could provide.  But, how could she reach them?

Read the rest of this entry »

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